Differential diagnosis of branchial cleft cysts

Approach to the differential diagnosis of branchial cleft cysts:

TypePrevalenceCourseLocationSymptom
First5%External auditory canal to parotidExternal auditory canal/parotidOtorrhea
Second90%Tonsil to low neckBetween sternocleidomastoid muscle and submandibular gland
ThirdRareHypopharynx to supraclavicularPost triangle, mandibular angle to mediastinum with 50% connecting to thymusThymic cyst
FourthRarePyriform sinus to thyroid to low neckPyriform sinus to left thyroidRecurrent thyroiditis