Pediatric Cyclophosphamide Induced Cystitis

  • Etiology: Seen in 70% of patients given high doses of cyclophsphamide
  • Imaging:
    — Diffuse bladder wall thickening with hyperemia
    — Debris and clots in bladder
  • DDX:
  • Complications:
  • Treatment:
  • Clinical: Severe hemorrhagic cystitis

Radiology Cases of Cyclophosphamide Induced Cystitis

CT of cyclophosphamide induced cystitis
Axial (above), coronal (below left) and sagittal (below right) CT with contrast of the abdomen shows diffuse thickening of the bladder wall and hyperemia of the bladder mucosa.
Transverse (above) and sagittal (below) US of the pelvis shows an extremely thick-walled bladder containing echogenic debris and clots.