Morquio’s Syndrome

  • Etiology: lysosomal storage disorders which have excessive accumulation of mucopolysaccharides secondary to deficiencies in lysosomal hydrolase enzymes responsible for degradation of mucopolysaccharides
  • Imaging: central beaking of vertebral bodies -> gibbus deformity, short wide ribs – canoe paddle ribs, universal platyspondyly unique to Morquio within mucopolysaccharidosis, flared pelvis, shortened broad bones
  • Clinical: Mucopolysaccharidoses Type IV

Cases of Morquio’s Syndrome