- Etiology: lysosomal storage disorders which have excessive accumulation of mucopolysaccharides secondary to deficiencies in lysosomal hydrolase enzymes responsible for degradation of mucopolysaccharides
- Imaging: beaked vertebral bodies, bullet shaped metacarpals, short trunked skeletal dysplasia from platyspondyly
— Osteoporosis
— Microcephaly
— Thick calvaria
— Wide ribs which are narrowed at costovertebral angle (oar shaped)
— Beaked oval vertebral bodies
— Thick trabeculae
— Femoral head dysplasia
— Coxa valga
— Narrow iliac wings
— Shortened tubular bones
— Tapering of 2nd -> 5th metacarpals
— Delayed myelination, atrophy, large Virchow-Robin spaces - Clinical:
— Mucopolysaccharidoses Type I = Hurler syndrome
— Mucopolysaccharidoses Type II = Hunter syndrome
— Mucopolysaccharidoses Type IV = Morquio syndrome
Radiology Cases of Mucopolysaccharidoses
Radiology Cases of Mucopolysaccharidoses Type I Hurler Syndrome

Radiology Cases of Mucopolysaccharidoses Type II Hunter Syndrome
Radiology Cases of Mucopolysaccharidoses Type IV Morquio Syndrome

Radiology Cases of Mucopolysaccharidoses Type VI
