A Pediatric Radiology textbook and Pediatric Radiology digital library
Mucopolysaccharidoses
Etiology: lysosomal storage disorders which have excessive accumulation of mucopolysaccharides secondary to deficiencies in lysosomal hydrolase enzymes responsible for degradation of mucopolysaccharides
Imaging: beaked vertebral bodies, bullet shaped metacarpals, short trunked dwarf from platyspondyly
Osteoporosis
Microcephaly
Thick calvaria
Wide ribs which are narrowed at costovertebral angle (oar shaped)
Beaked oval vertebral bodies
Thick trabeculae
Femoral head dysplasia
Coxa valga
Narrow iliac wings
Shortened tubular bones
Tapering of 2nd -> 5th metacarpals
Delayed myelination, atrophy, large Virchow-Robin spaces