Pediatric Rathke Cleft Cyst

  • Etiology: Non-neonplastic cyst arising from remnants of squamous epithelium of Rathke’s cleft or pars intermedia of adenohypophysis
  • Imaging MR:
    — Usually located between pars anterior and pars posterior
    — Intra or suprasellar cyst without calcification or enhancement
    — Variable cyst content – mucous (T1 bright), serous (T1 dark) and possible blood products (T2 dark)
    — Usually less than 3 millimeters in diameter
    — With or without small intracystic nodules
  • DDX: Pituitary microadenoma
  • Complications:
  • Treatment: None
  • Clinical: Normal variant

Radiology Cases of Rathke Cleft Cyst

MRI of Rathke cleft cyst
Sagittal T1 MRI with contrast of the sella shows an oval non-enhancing lesion located between the anterior and posterior aspects of the pituitary gland.