Sickle Cell Anemia

  • Etiology: sickling of red blood cells
  • Imaging:
    — Marrow hyperplasia: long bones – widening of metaphyses / widening of trabeculae / thinning of cortex / osteopenia, skull – widened diploic spaces
    — Bone infarct: in proximal femur / proximal humerus / distal femur / proximal tibia, lucency + sclerosis of medullary bone, cortical bone infarct -> periosteal reaction, H-shaped vertebra due to infarct of central part of vertebral body
    — Infection: due to Staphylococcus aureus + salmonella, see erosions / lysis / periosteal reaction

Cases of Sickle Cell Anemia