DDX of intussusception

Approach to the DDX of intussusception:

  • 90% of intussusceptions are idiopathic and are due to hypertrophied Peyer’s patches serving as the lead point
  • In patients > 3 years old or in patients with recurrent intussusception, consider and look for a pathological cause of a lead point such as Meckel’s diverticulum, lymphoma, or polyps
  • If intussusception is < 3 cm in diameter on a transverse US image it is most likely a transient small bowel-small bowel intussusception, so rescan the patient in 10 minutes to see if it has gone away