Acute Disseminated Encephalomyelitis

  • Etiology: immune mediated leukoencephalopathy / demyelination involving brain, may involve cord
  • Imaging: plaques shorter than two vertebral body segments, involve less than half cross-sectional area of cord, peripherally located in dorsal and lateral columns, variable enhancement, brain lesions also
  • Clinical: seen post-viral infection (measles or influenza) or post-vaccination (10%), transient, monophasic, responds to steroids, associated with Ebstein Barr virus / cytomegalovirus / mycoplasma pneumonia

Cases of Acute Disseminated Encephalomyelitis