- Etiology: primary malignant bone tumor
- Imaging:
— Location: tibial diaphysis, originates in cortex
— Lytic or blastic: lytic
— Matrix: (chondroid, osseous, fibrous)
— Zone of transition: (wide, narrow)
— Periosteal new bone or cortical destruction: none
— Additionally:
— Radiograph: multilocular, slightly expansile, excentric, osteolytic, cortical lesion, no periosteal reaction
— CT: lytic lesion, excentric epicenter in cortex, may have calcifications
— MR: solitary lobulated lesion or multiple nodules, T1WI decreased signal, T2WI increased signal, may have fluid-fluid levels, marked enhancement - DDX: osteofibrous dysplasia
- Clinical: teen + young adults
Pediatric Imaging 