Pediatric Adrenocortical Carcinoma

  • Etiology: Malignant adrenal neoplasm that may be hormonally active
  • Imaging:
    — Solid adrenal mass
  • Imaging Radiograph: Increased bone age
  • DDX:
  • Complications:
  • Treatment:
  • Clinical: Presents with Cushing syndrome (30%), virilization and precocious puberty (22%), or feminization (10%)

Radiology Cases of Adrenocortical Carcinoma

US of adrenocortical carcinoma.
Transverse and sagittal US of the left kidney shows a large solid left adrenal mass.
CT of adrenocortical carcinoma
Axial CT with contrast of the abdomen shows a large solid mass mass in the left adrenal gland that has heterogenous enhancement.
CT of adrenocortical carcinoma
Axial (above) and coronal (below) CT without contrast of the abdomen show a large solid nodular mass in the region of the right adrenal gland. The left adrenal gland is normal.

Gross Pathology Cases of Adrenocortical Carcinoma

Pathological image of adrenocortical carcinoma
Sectioned gross pathological image shows a solid mass filling and expanding the left adrenal gland.