Agenesis of Corpus Callosum

  • Etiology: abnormality of ventral induction, order of growth is genu -> body -> splenium (front to back), Bundles of Probst run front to back instead of crossing midline
  • Imaging: parallel lateral ventricles on axial images, Viking horn / everted lateral ventricles on coronal images, colpocephaly, high riding third ventricle
  • Clinical: associated with pericallosal lipoma which arise from persistence + maldifferentiation of meninx primitiva, Dandy Walker malformation, encephalocele

Radiology Cases of Agenesis of Corpus Callosum