Aspergillosis

  • Etiology: Aspergillus infection whose manifestation is dependent on patient’s immune status
  • Allergic Bronchopulmonary Aspergillosis (ABPA)
    Etiology: hyperimmune status – hypersensitivity reaction associated with asthma
    Imaging: affects airways, mucoid impaction with central bronchiectasis – “gloved finger”
    Clinical: uncommon in children
  • Aspergilloma (Fungus ball / mycetoma)
    Etiology: normal immunity
    Imaging: affects / infects pre-existing cavity
    Complications: pulmonary hemorrhage
  • Invasive aspergillosis
    Etiology: hypoimmune status / immunocompromised
    Imaging: affects parenchyma – bronchocentric / angiocentric lesion, halo sign – parenchymal density surrounded by irregular ground glass density (hemorrhagic halo), air crescent sign – central necrosis detached from wall
    Complications: disease in brain, liver, kidneys, spleen

Cases of Aspergillosis