- Etiology: Aspergillus infection whose manifestation is dependent on patient’s immune status
- Allergic Bronchopulmonary Aspergillosis (ABPA)
— Etiology: hyperimmune status – hypersensitivity reaction associated with asthma
— Imaging: affects airways, mucoid impaction with central bronchiectasis – “gloved finger”
— Clinical: uncommon in children - Aspergilloma (Fungus ball / mycetoma)
— Etiology: normal immunity
— Imaging: affects / infects pre-existing cavity
— Complications: pulmonary hemorrhage - Invasive aspergillosis
— Etiology: hypoimmune status / immunocompromised – post chemotherapy or stem cell transplant
— Imaging: affects parenchyma – bronchocentric / angiocentric lesion, halo sign – parenchymal density surrounded by irregular ground glass density (hemorrhagic halo), air crescent sign – central necrosis detached from wall
— Complications: 25-50% has systemic hematogenous dissemination to brain, liver, spleen, kidneys
— DDX: other fungi – Candidiasis, Cryptococcus
Radiology Cases of Aspergillosis
Radiology Cases of Allergic Bronchopulmonary Aspergillosis (ABPA)
Radiology Cases of Aspergilloma
Radiology Cases of Invasive Aspergillosis


