Pediatric Bone Metastases

  • Etiology: leukemia, lymphoma, neuroblastoma, Wilms tumor
  • Radiograph: lytic lesions when due to solid tumors, loss of vertebral body height in leukemia
  • Complications: pathologic fracture
  • Clinical: may be painful

Radiology Cases of Bone Metastases

Radiology Cases of Neuroblastoma Bone Metastases

Radiograph of neuroblastoma bone metastases to the femur
AP radiograph of the femurs shows a mottled appearance to both femurs with multiple lytic lesions noted in the femurs with associated periosteal reaction, more prominent on the left than the right.
Radiograph of bone metastases from neuroblastoma
AP radiographs of the humerus (above) and radius and ulna (below) show lesions involving the proximal humeral diaphysis, entire radial diaphysis and proximal ulna diaphysis all of which are lytic in appearance and having a wide zone of transition and associated faint periosteal reaction.
CT of adrenal neuroblastoma with bone metastases
Coronal (left) and axial (above right) CT with contrast of the abdomen show a large low density faintly calcified mass arising from the right adrenal gland. Axial image of the pelvis in bone windows (below) shows multiple lytic bone lesions throughout the iliac wings and sacrum.