Coloboma

  • Etiology: Incomplete closure of choroid fissure
  • DDX:
  • Complications:
  • Treatment:
  • Clinical: Associated with CHARGE syndrome, Meckel Gruber syndrome, Trisomy 13, Rubenstein-Taybi syndrome, Waardenburg syndrome

Radiology Cases of Coloboma

Axial (above) and coronal (below) CT with contrast of the orbits show bilaterally small orbits containing small optic nerves and small extraocular muscles. There is also bilaterally calcification in the center of the vitreous of the globes and colobomatous cysts inferolaterally within the orbits.
MRI of pediatric coloboma
Axial T2 (above) and T1 (below) MRI without contrast of the brain shows in the left orbit a small pouch-like fluid-filled discontinuity of the posterior left orbit.