Copper Deficiency

• Etiology: Lack of copper which is required for endochondral bone and collagen
• Imaging:
  — Symmetric changes of metaphyseal irregularity and lucency
  — Loss of cortical sharpness
  — Midshaft bowing
  — Metaphyseal cupping
  — Metaphyseal spurs in medial distal femurs and ulna
  — Osteopenia
  — Increased density in zone of provisional calcification
  — Delayed bone age
• DDX: Child abuse
• Complications:
• Treatment: Copper supplementation
• Clinical:

Radiology Cases of Copper Deficiency