A Pediatric Radiology textbook and Pediatric Radiology digital library
Cytomegalovirus Encephalitis
Etiology: transplacental infection of CMV
Imaging: — If infection is early – before 18 weeks – see migration anomaly (lissencephaly), polymicrogyria, cerebellar hypoplasia — If infection is late – see destructive lesions, germinolysis, myelination delay — Large ventricles due to encephalomalacia, periventricular calcifications + lenticulostriate calcifications, intraparenchymal hemorrhage, microcephaly
Clinical: pneumonia, hepatosplenomegaly, blueberry muffin lesions on skin = petechia, purpura, mounded lesions of extramedullary hematopoesis