Pediatric Epidermolysis Bullosa

• Etiology: Genetic condition characterized by blistering of the skin
• Imaging Gastrointestinal:
  — Limited to muscosa of gastrointestinal tract and primarily the esophagus
  — Acutely see submucosal bullae and chronically see esophageal webs
• Imaging Genitourinary:
  — Scarring of glans penis or vaginal vestibule with associated urethral strictures can cause urinary tract outflow obstruction and hydroureteronephrosis
• Imaging Musculoskeletal:
  — Blistering and scarring of skin can case fusion of fingers and toes
  — Contractures of multiple joints
  — Acro-osteolysis
• DDX:
• Complications:
• Treatment:
• Clinical: Can be limited to palms of hands and soles of feet or can involve whole body

Radiology Cases of Epidermolysis Bullosa