Pediatric Ganglioglioma

  • Etiology: Neoplasm composed of ganglion cells and neoplastic glial elements
  • Imaging MRI:
    — Sharply demarcated supratentorial cystic mass with calcification
    — Slow growth (bone erosion)
    — Other sites include medulla and conus medullaris
  • DDX:
  • Complications:
  • Treatment: Surgical
  • Clinical:
    — Most common cause of chronic temporal lobe epilepsy
    — Often presents with symptoms rather than mass effect

Radiology Cases of Ganglioglioma

MRI of ganglioglioma
Coronal T2 (above left), FLAIR (above right) and T1 MRI with contrast (below) of the brain show a round cystic lesion in the medial aspect of the left temporal lobe that has an enhancing mural nodule superiorly.
CT and MRI of pediatric ganglioglioma
Axial CT without contrast of the brain (above left) shows a heterogeneously calcified large solid mass in the left thalamus. Axial FLAIR (above right) and coronal T1 without contrast (below left) MRI of the brain show the mass to be poorly circumscribed and to extend into the mesencephalon. Axial T1 MRI with contrast (below right) shows heterogenous contrast enhancement.