Gorlin Syndrome

  • Etiology: Nevoid basal cell carcinoma
  • Imaging:
    — Falx calcification
    — Multicentric odontogenic keratocyst
    — Bifid ribs
  • DDX:
  • Complications:
  • Treatment:
  • Clinical:
    — Radiation sensitive so don’t radiate
    — Associated with medulloblastoma (10%) and meningioma and ovarian and cardiac fibromas

Radiology Cases of Gorlin Syndrome

CT of odontogenic keratocyst in Gorlin syndrome
Axial (above), coronal (below left) and sagittal (below right) CT without contrast of the face shows a lytic, expansile lesion in the right maxilla displacing the second right premolar tooth anterolateraly. There was no bone destruction or associated soft tissue mass.