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Hepatic Infantile Hemangioma
Etiology: congenital vascular tumor
3 subtypes
— Multifocal: clinically asymptomatic with skin hemangiomas, GLUT1(+), small without necrosis, proliferation then involution
— Focal: clinically have congestive heart failure, GLUT1(-), large with necrosis, involute by 1 year
— Diffuse: clinically have congestive heart failure + hypothyroidism + compartment syndrome, GLUT1(+), hepatomegaly with multiple masses, complicated clinical course
CT: can have fine / granular calcification, arterial phase shows peripheral nodular enhancement of mass that enhances more than the liver with centripedal fill in during delayed phase
Clinical: rarely has elevated AFP (15%), 30% diagnosed in first month / 90% diagnosed in first 6 months
Cases of Hepatic Infantile Hemangioma
Coronal T1 weighted MRI without (left) and with (right) contrast of the abdomen shows a round, well-circumscribed lesion in the right lobe of the liver that has ring enhancement and that was seen to fill in on delayed images.Axial CT with contrast of the abdomen in the arterial phase (upper left) and then 1, 7 and 15 minutes later (lower right) shows a large liver mass that has an enhancing rim and a low density center which slowly filled in on delayed images.