- Etiology:
- Imaging MRI:
— T2WI: Liver is hypointense (dark) and spleen is isointense and is normal in size - DDX:
- Complications:
- Treatment:
- Clinical:
Hemochromatosis neonatal
- Etiology:
- Imaging: Combination of:
— Severe liver disease – cirrhosis or fulminant liver failure and iron deposition in liver and other organs
— Sparing of reticuloendothelial system – no siderosis in spleen or marrow or lymph nodes
— Extrahepatic siderosis in pancreas and myocardium and thyroid and minor salivary glands - DDX:
- Complications:
- Treatment:
- Clinical:
— Common cause of neonatal liver failure
— Clinically different from hereditary hemochromatosis
— To diagnose this you need neonatal liver failure and extrahepatic siderosis as severe hepatic siderosis is not enough to make diagnosis