Pediatric Fibrolamellar Hepatocelluar Carcinoma

  • Etiology: No history of cirrhosis or viral hepatitis or alcohol abuse
  • Imaging:
    — No cirrhosis
    — Calcification in 70%
  • Imaging MRI:
    — T1WI: Central scar hypointense with radiating fibrous septae
    — T1WI post contrast: Lesion does not enhance
    — T2WI: Central scar hypointense with radiating fibrous septae
  • DDX:
  • Complications:
  • Treatment:
  • Clinical:
    — Second most common hepatic malignancy in children
    — Seen in adolescents and young adults with normal AFP

Radiology Cases of Fibrolamellar Hepatocelluar Carcinoma

US of hepatocellular carcinoma
Sagittal US of the liver shows it to be enlarged and multinodular in appearance.

Radiology Cases of Lung Metastases in Fibrolamellar Hepatocellular Carcinoma

CXR of lung metastases in fibrolamellar hepatocellular carcinoma
CXR AP shows multiple large round non-calcified lesions in the lungs bilaterally.