Herpes Simplex Virus-1 Encephalitis

  • Etiology: necrotizing hemorrhagic encephalitis, localized in limbic system
  • Imaging: bilateral + asymmetric temporal encephalitis – affects mesial temporal lobes early, can enhance
  • CT: normal or diffuse mild edema / swelling
  • MRI: diffuse, T2 hyperintense, especially in gray matter, variable contrast enhancement
  • Clinical: in older child / adult

Cases of Herpes Simplex Virus-1 Encephalitis