Histoplasmosis

  • Etiology: Histoplasma capsulatum, endobronchial spread
  • Imaging: hilar lymphadenopathy with calcification, bilateral nodules of various sizes (but bigger than miliary in size) with irregular margins, tree in bud appearance (endobronchial spread)
  • DDX: Tuberculosis – histoplasmosis has greater number of parenchymal lesions

Cases of Histoplasmosis

CXR of histoplasmosis
CXR PA and lateral shows bilateral hilar lymphadenopathy, right greater than left, and small miliary nodules throughout the lungs.
CT of histoplasmosis
CT with contrast of the chest shows bilateral hilar adenopathy.