Hypervitaminosis A

  • Etiology: overdose of Vitamin A
  • Imaging: cortical thickening most commonly involves ulna + metatarsals followed by clavicle and then tibia + fibula, premature fusion of epiphyses, takes weeks – months to resolve radiographically
  • DDX: Infantile cortical hyperostosis which involves mandible + clavicle + ulna

Radiology Cases of Hypervitaminosis A

Radiograph of hypervitaminosis A
AP radiograph of the bilateral femurs (above) shows diffuse periosteal reaction along the lateral borders of the femoral diaphyses, left greater than right. Lateral radiograph of the forearm (below) shows dense periosteal reaction along the posterior aspect of the ulna.