Hereditary Hypophosphatemic Rickets

Etiology: deficiency of phosphorous
Imaging: metaphyseal cupping, genu varum (can also be valgum)
US: nephrocalcinosis

Radiology Cases of Hereditary Hypophosphatemic Rickets

Radiograph of hypophosphatemic rickets — AP radiograph of the lower extremities shows bowing of the bilateral femurs and tibias and widening of the physis medially in the bilateral distal femurs and proximal tibias.

Radiograph of hypophosphatemic rickets — AP radiograph of the knees (above) shows widening of the physis medially in the bilateral distal femurs and proximal tibias while AP radiograph of the wrists (below) shows cupping of the distal ulna metaphyses bilaterally.

Radiograph of hypophosphatemic rickets — AP radiograph of the knees (above) shows cupping of the metaphyses in the bilateral distal femurs and proximal tibias while AP radiograph of the wrists (below) shows cupping of the distal radius and ulna metaphyses bilaterally.