Infantile Cortical Hyperostosis

  • Etiology: unknown
  • Imaging: asymmetrical cortical thickening involving #1 mandible, #2 clavicle, #3 ulna
  • Clinical: present before 9 weeks old, unusual after 6 months old, can have irritability / acute pain / soft tissue swelling, elevated alkaline phosphatase

Radiology Cases of Infantile Cortical Hyperostosis

Radiograph of infantile cortical hyperostosis of clavicle
CXR AP shows marked periosteal reaction involving the left clavicle which is thickened and hyperostotic in appearance. The right clavicle is normal.