Macrophthalmia

  • Etiology: juvenile glaucoma (buphthalmos), congenital myopia
  • Imaging: enlarged globe
  • Clinical: seen in neurofibromatosis type 1 + Sturge Weber syndrome

Radiology Cases of Macrophthalmia

MRI of macrophtalmia and optic pathway glioma in neurofibromatosis type I
Axial (above) and coronal (below) T2 MRI without contrast of the brain shows the left globe is larger than the right globe. The optic nerves bilaterally are thickened and tortuous.