Pediatric Mesial Temporal Sclerosis

  • Etiology: Controversial – is it result of temporal lobe epilepsy or vice versa
  • Imaging MRI:
    — Atrophy of hippocampus and amygdala and fornix and mamillary body
    — T1WI: Hypointense
    — T2WI: Hyperintense
  • Imaging PET FDG: Low metabolism
  • DDX:
  • Complications: Causes chronic refractory seizures
  • Treatment:
  • Clinical: 15% bilateral

Radiology Cases of Mesial Temporal Sclerosis

MRI of mesial temporal sclerosis
Coronal T2 (above) and FLAIR (below) MRI of the brain shows atrophy and sclerosis represented by bright T2 signal of the left hippocampus which also showed low metabolism on PET imaging.