Microphthalmia

  • Etiology: congenital rubella, cytomegalovirus, persistent hyperplastic primary vitreous, retinopathy of prematurity, surgery, trauma, infection
  • Imaging: small globe, poorly developed orbit

Radiology Cases of Microphthalmia

Axial (above) and coronal (below) CT with contrast of the orbits show bilaterally small orbits containing small optic nerves and small extraocular muscles. There is also bilaterally calcification in the center of the vitreous of the globes and colobomatous cysts inferolaterally within the orbits.
MRI of retinopathy of prematurity
Axial T2 MRI without contrast of the brain shows small orbits bilaterally. Heterogeneity of the vitreous humor could not be assessed for on the other sequences due to patient motion.