Neuroblastoma Stage 4S or Neuroblastoma Stage MS

  • Etiology: Localized primary tumor and disease dissemination limited to liver and skin and less than 10% bone marrow but not bone
  • Imaging:
    — Primary tumor often small
    — Massive hepatic and or skin metastases
  • DDX:
  • Complications:
  • Treatment: Often have spontaneous regression without therapy
  • Clinical:
    — Age less than 1 year
    — Better prognosis
    — Blueberry muffin skin lesions in 33%

Radiology Cases of Neuroblastoma Stage 4S or Neuroblastoma Stage MS

CT of neuroblastoma Stage 4S
Coronal (above left), sagittal (above right) and axial (below left) CT with contrast of the abdomen show a large left-sided suprarenal mass which is calcified and displaces the right kidney inferiorly and posterior. Axial CT of the pelvis (below right) shows the small right gluteal subcutaneous soft tissue nodule.