Pediatric Neurofibromatosis Type 2

  • Etiology: mutations in NF2 gene result in predisposition to tumor formation throughout nervous system
  • Imaging: multiple cranial nerve schwannomas (vestibular schwannoma most common), meningiomas, spinal ependymomas, spinal nerve schwannomas
  • Clinical: lack of skin stigmata of neurofibromatosis type 1

Radiology Cases of Neurofibromatosis Type 2

Radiology Cases of Meningioma in Neurofibromatosis Type 2

MRI of a meningioma in a patient with neurofibromatosis Type 2
Coronal T1 MRI with contrast of the brain shows a round, solid, homogeneously enhancing intracranial lesion above the left orbit that is in continuity with the meninges and which appears to have a dural tail. The patient also had multiple schwannomas.
MRI of a meningioma in a patient with neurofibromatosis Type 2
Coronal (above) and axial (below) T1 MRI with contrast of the brain show an oval, solid, homogeneously enhancing parafalcine lesion that is in continuity with the meninges and which appears to have a dural tail.

Radiology Cases of Acoustic Neuromas in Neurofibromatosis Type 2

MRI of acoustic schwannomas in a patient with neurofibromatosis Type 2
Axial T1 MRI with contrast of the brain shows bilateral homogeneously enhancing masses in the cebrebellopontine angles. The patient also had an intracranial meningioma.