Osteoid Osteoma

  • Etiology: Benign tumor containing osteoid in a stroma of loose vascular connective tissue
  • Imaging Bone scan:
    — Increased uptake
    — Useful for intraoperative localization
  • Imaging Extra-articular Radiograph:
    — Classicly: Lucent nidus with surrounding sclerosis and periosteal new bone
    — Less than 2 centimeters in size
    — Femur or tibia or humerus most common
    — Usually in cortex
    — Central calcification
    — Small radiolucent nidus with reactive sclerosis
    — Periosteal new bone
    — If in spine posterior elements have sclerotic pedicle on ipsilateral side and scoliosis convex away from side of tumor
  • Imaging Extra-articular CT: Lucent nidus surrounded by focal cortical thickening
  • Imaging Extra-articular MRI:
    — T1WI without fat saturation: Bright rim
    — T1WI post contrast: Cortical thickening and enhancing nidus with bright early arterial phase enhancement
    — T2WI with fat saturation: Hyperintense edema surrounding nidus and hypointense surrounding sclerosis
  • Imaging Intra-articular Radiograph: Normal with no periosteal reaction or cortical thickening
  • Imaging Intra-articular CT: Tiny radiolucent nidus which may be nearly inconspicuous and which may have central calcification
  • Imaging Intra-articular MRI:
    — T2WI with fat saturation: Geographic marrow edema and joint effusion with synovitis
  • DDX:
  • Complications:
  • Treatment:
  • Clinical:
    — Night time pain relieved by NSAIDs
    — Age range 6 – 17 years old
    — In spine causes painful scoliosis

Radiology Cases of Osteoid Osteoma

Radiology Cases of Osteoid Osteoma in Spine

Radiograph and CT of osteoid osteoma of the spine
AP radiograph of the thoracic spine shows an indistinct margin of the left T10 pedicle and mild scoliosis convex right. Axial CT without contrast of the T10 vertebral body with coronal and sagittal 2-D reconstructions shows a small round lucent nidus with central calcification in the left T10 pedicle surrounded by sclerosis.
Plain film and CT and bone scan of osteoid osteoma of the spine
AP radiograph of the thoracic spine (left upper) shows a mild curvature of the spine convex right and the left pedicle of the T12 vertebral body is difficult to visualize. Axial CT without contrast of the T12 vertebral body (right upper) shows a lesion with a lucent nidus surrounded by a sclerotic rim in the left pedicle of the T12 vertebral body. Pinhole (left lower) and whole body (right lower) images from a nuclear medicine bone scan show focally increased radiotracer localization in the left pedicle of the T12 vertebral body and a curvature of the spine convex right.

Radiology Cases of Extra-articular Osteoid Osteoma

CT and MRI of osteoid osteoma
AP radiograph of the femur (above left) shows tremendous cortical thickening of the femoral diaphysis. Axial CT without contrast of the femur (above right) shows a round lucent lesion with central calcification within the center of the tremendously thickened cortex. Axial T2 MRI (middle) through the lesion shows a tremendous amount of edema surrounding the thickened cortex of the right femur. Coronal T1 MRI without (below left) and with (below right) contrast of the femur shows the lesion to enhance.

Radiology Cases of Intra-articular Osteoid Osteoma

Radiograph and CT of osteoid osteoma of the femur
AP radiograph of the pelvis shows a round lucent lesion in the right femoral neck. Coronal 2D reconstruction and axial CT without contrast of the pelvis shows the lesion to be centered in the cortex, to have a central calcification in a radiolucent nidus, and to be surrounded by reactive sclerosis. There is also a left hip effusion on the lower left CT image.