Persistent Hyperplastic Primary Vitreous

  • Etiology: failure of normal regression of embryonic hyaloid vascular system
  • Imaging: small globe, unilateral or bilateral, not calcified, primary vitreous becomes condensed into narrow triangular retrolental vascular tuft of tissue (Cloquet’s canal)
  • Clinical: leukocoria

Cases of Persistent Hyperplastic Primary Vitreous