Peutz-Jeghers Syndrome

  • Etiology: GI hamartomas
  • Complications: malignant transformation rare, life time cancer risk > 90% (pancreas + breast)
  • Clinical: skin / mucosal pigmentation

Cases of Peutz-Jeghers Syndrome

Small bowel follow through of Peutz-Jeghers syndrome
AP (left) and lateral (right) spot images from an upper GI show several round filling defects in the proximal jejunum, the most notable being in the left-most aspect of the AP image.