Pediatric Plexiform Neurofibroma Etiology: heterogeneous mixture of Schwann cells / perineural cells / fibroblastsImaging: often causes sphenoid wing erosion (dysplasia)Clinical: almost exclusively seen in neurofibromatosis type 1 Radiology Cases of Plexiform Neurofibroma CXR PA shows a large soft tissue mass in the apex of the right lung which causes thinning of the right 1st-5th ribs posteriorly. CT without contrast of the chest shows multiple small nodules throughout the soft tissues of the chest wall. CXR PA and lateral shows a right apical thoracic mass with associated rib thinning that had rapidly increased in size in a short interval. Axial CT without contrast of the chest better defined the right apical mass and demonstrated multiple serpiginous nodules in the soft tissues of the right anterior chest wall. CXR shows a posterior mediastinal mass. Coronal and sagittal T1 MRI without contrast of the thoracic spine shows dural ectasia. Clinical Cases of Plexiform Neurofibroma Clinical image shows extensive, large soft tissue masses involving the right arm and chest wall.