Pediatric Post-transplant Lymphoproliferative Disorder

  • Etiology: Risk factors for developing it include high levels of immunosuppression, type of organ transplanted, young age at transplant, Ebstein Barr virus status
  • Imaging:
    — Extranodal involvement most common in 80%
    — Distal small bowel most common site (jejunum or ileum) followed by colon greater than stomach greater than esophagus
  • DDX:
  • Complications:
  • Treatment:
  • Clinical:
    — Most common malignancy in children after organ transplantation
    — More frequent in multiorgan transplants

Radiology Cases of Post-transplant Lymphoproliferative Disorder