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Prostaglandin E Induced Gastritis
Etiology: prostaglandin E – keeps patent ductus arteriosus open in patent ductus arteriosus dependent congenital heart diseases (pulmonary atresia, hypoplastic left heart syndrome) and can cause gastric mucosal hypertrophy and gastric outlet obstruction
UGI: narrowing of the pyloric channel
US: thickening of the echogenic central gastric mucosa with normal diameter of the pyloric muscle outside of it
DDX: hypertrophic pyloric stenosis
Cases of Prostaglandin E Induced Gastritis
Two lateral images from an upper GI (above) show persistent narrowing of the pylorus causing relative gastric outlet obstruction. Sagittal (left below) and transverse (right below) US of the pylorus shows the central echogenic gastric mucosa to be thickened and the pyloric muscle outside of it to be normal in diameter. The patient was also noted to be malrotated.