Prostaglandin Osteopathy

  • Etiology: prostaglandin E1 used to keep ductus open
  • Imaging: generalized cortical hyperostosis
  • DDX: Caffey’s disease which is not reversible like prostaglandin osteopathy

Radiology Cases of Prostaglandin Osteopathy

Radiograph of prostaglandin osteopathy
AP (left) and lateral (right) radiographs of the lower extremity shows thick, dense periosteal reaction along the femur, tibia, and fibula.