Prostaglandin Osteopathy Etiology: prostaglandin E1 used to keep ductus openImaging: generalized cortical hyperostosisDDX: Caffey’s disease which is not reversible like prostaglandin osteopathy Radiology Cases of Prostaglandin Osteopathy AP (left) and lateral (right) radiographs of the lower extremity shows thick, dense periosteal reaction along the femur, tibia, and fibula.
Pediatric Imaging 