• Etiology: primitive neuroectodermal tumor
  • Imaging: normal globe size, unilateral or bilateral, can be calcificed, intraocular retinal mass, can cause retinal detachment
  • Complications: trilateral retinoblastoma = pineal involvement = pineoblastoma simultaneous or metachronous to retinoblastoma, quadrilateral retinoblastoma = trilateral retinoblastoma + hypothalamic tumor
  • Clinical: leukocoria

Radiology Cases of Unilateral Retinoblastoma

MRI of retinoblastoma
Axial T1 without contrast (above left), coronal T2 (above right), axial T1 (below left) and coronal T1 (below right) MRI with contrast of the orbits show a large heterogenous solid mass arising from the posterior aspect of the right globe that enhances with contrast. There was no extension to the right optic nerve.

Radiology Cases of Bilateral Retinoblastoma

MRI of bilateral retinoblastoma
Axial T1 MRI with contrast of the orbits shows solid enhancing masses arising from the posterior aspect of the globes bilaterally. There was no extension into the optic nerves.