Schizencephaly

  • Etiology: abnormality of neuronal migration
  • Imaging: cleft extending from surface of cortex to lining of ventricle, gray matter forms banks of schizencephaly cleft, if cleft walls are separated by CSF = open lip, if cleft walls are in apposition = closed lip, irregular ependymal lining
  • Clinical: open lip – more common than closed lip, open lip more commonly bilateral, closed lip more commonly unilateral

Cases of Schizencephaly