Pediatric Secondary Hyperparathyroidism

  • Etiology: decreased serum calcium -> increased PTH levels, most common cause is renal disease -> decreased vitamin D conversion to active form -> renal osteodystrophy
  • Imaging: loss of provisional zone of calcification, widened growth plates, frayed metaphyses, coarsening of trabeculae, demineralization, cortical thinning
  • Clinical: secondary hyperparathyroidism

Radiology Cases of Secondary Hyperparathyroidism

Radiograph of secondary hyperparathyroidism
AP radiograph of the knee shows widening of the distal physis of the femur and the proximal physis of the tibia and fibula and frayed metaphyses in the same areas.