Pediatric Sickle Cell Disease Neurological

  • Etiology: Sickle cell disease
  • Imaging:
  • DDX:
  • Complications: 11% of children with sickle cell disease not receiving primary stroke prevention therapy will have a stroke by 20 years old
  • Treatment:
  • Clinical: Most common inherited blood disorder in USA

Radiology Cases of Sickle Cell Disease Neurological

MRA of sickle cell disease causing near total occlusion of the left internal carotid artery
AP MRA of the neck with contrast (above) shows near total occlusion of the left internal carotid artery. AP MRA of the brain with contrast (below) shows the left internal carotid artery to be small in caliber and to have a beaded appearance. The left middle carotid artery is reconstituted throug the anterior communicating artery.