Takayasu Arteritis

  • Etiology: large vessel vasculitis, chronic idiopathic granulomatous inflammation of large arteries
  • Imaging: affects thoracic + abdominal aorta simultaneously along with renal arteries / pulmonary artery / coronary arteries, see thickened enhancing wall of aorta + its branches with luminal narrowing, +/- thrombus, diffuse or focal aneurysms
  • CT: calcification
  • MR: increased T2 signal is sign of active inflammation
  • Complications: vascular stenosis / occlusion / aneurysm (less common)
  • Clinical: presents in adolescence, has 3 phases – early prepulseless phase, vascular inflammatory phase, late occlusive phase

Cases of Takayasu Arteritis