Tamm Horsfall Proteins

  • Etiology: Tamm-Horsfall proteins are physiologically excreted by the renal tubular epithelium
  • Imaging US: Concentrated Tamm-Horsfall proteins in renal pyramids may mimic nonobstructing renal stones
  • DDX: Renal stones, nephrocalcinosis
  • Complications:
  • Treatment:
  • Clinical: Commonly seen on neonatal renal ultrasound and resolve by the end of the neonatal period

Radiology Cases of Tamm Horsfall Proteins

US of Tamm Horsfall proteins
Sagittal US of the kidneys shows multiple echogenic lesions in the renal pyramids bilaterally which resolved on a repeat ultrasound performed one month later.
US of Tamm Horsfall proteins
Sagittal US of the kidneys shows multiple round echogenic foci in the renal pyramids bilaterally.