Pediatric Testicular Epidermoid Cyst

  • Etiology: Benign lesion with layers of keratinous debris lined with keratinizing squamous epithelium
  • Imaging US:
    — Non-vascular and well-marginated intratesticular mass
    — May have characteristic lamellated onion skin or whorled appearance with alternating hyperechoic and hypoechoic rings
    — Some may have target appearance with halo of hypoechogenicity and central hyperechoic region
  • DDX: Testicular germ cell tumor which tends to show vascularity, testicular teratoma, focal intratesticular granulomatous disease such as tuberculosis, focal testicular hemorrhage
  • Complications:
  • Treatment: Orchiectomy versus tumor sparing surgery
  • Clinical:
    — Present with painless testicular mass
    — Usually in second to fourth decades
    — Most common benign testicular neoplasm

Radiology Cases of Testicular Epidermoid Cyst

US of testicular epidermoid cyst
Transverse (above) and sagittal (below) color doppler US of the right testicle shows an intratesticular, round, well-marginated, hypovascular lesion which has a hyperechoic center and a hypoechoic perhiphery (target sign) and overall a whorled appearance.