Toxoplasmosis Encephalitis

• Etiology: Toxoplasma gondii causes ependymitis which leads to cerebrospinal fluid flow obstruction through aqueduct of Sylvius which leads to hydrocephalus, calcifications in basal ganglia and periventricular white matter and cortex
• Imaging: Severity dependent on timing
  — Early second trimester: In contrast to cytomegalovirus hydrocephalus is frequent and migrational abnormality is rare, also see porencephaly, periventricular vasculitis and necrosis, nodular periventricular and parenchymal calcifications that may resolve with treatment
• Third trimester: Mild atrophy, rare hydrocephalus, smaller amount of calcification
• DDX: Cytomegalovirus – Cytomegalovirus calcifications are perventricular while toxoplasmosis calcifications are random, in cytomegalovirus globes are normal and in toxoplasmosis globes are abnormal
• Complications:
• Treatment:
• Clinical:

Radiology Cases of Toxoplasmosis Encephalitis