Newborn with abdominal distension and failure to pass meconium

Surgical image of Hirschsprung disease
Surgical image shows a visible transition zone in the mid sigmoid colon with the forceps at the actual site of transition. The sigmoid colon (to the right) is dilated and had ganglion cells on biopsy. The rectum (to the left), descending into the pelvis, is not dilated and had no ganglion cells on biopsy.

The diagnosis was Hirschsprung disease.