Preschooler with recurrent episodes of respiratory distress over several years

CXR of chronic granulomatous disease
Initial CXR AP (above) shows an opacity in the medial aspect of the right lower lobe which took a year to resolve radiographically. CXR AP obtained 2 years after the initial CXR (below left) shows a dense opacity in the medial aspect of the right upper lobe which was only slightly reduced in size on a CXR obtained a year later (below right).

The diagnosis was chronic granulomatous disease.