Infant with in-utero exposure to a sexually transmitted disease Pediatric Imaging Musculoskeletal March 22, 2025January 16, 2025 AP radiograph of the lower extremity shows diffuse periostitis of the tibia and some destructive changes on the medial proximal metaphysis of the tibia (Wimberger’s sign). The diagnosis was syphilis. Related Published March 22, 2025January 16, 2025